Machine Learning Street Talk (MLST) · 22 June 2026 · 53 min

He won a Nobel here for AlphaFold. Then he left. - John Jumper

Protein foldingAlphaFold architectureStructural biologyMachine learningDrug discoverySE(3) invarianceDiffusion modelsAI for scienceHybrid AI modelsScientific predictionBiological dataTraining scientistsGlobal research access

This episode features John Jumper, co-creator of AlphaFold, discussing the breakthrough in protein structure prediction that won the 2024 Nobel Prize in Chemistry. Jumper explains the technical innovations behind AlphaFold, its impact on biology and drug discovery, and his recent move to Anthropic. The episode also highlights how AlphaFold is empowering researchers globally, including efforts to train scientists in Africa.

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